LASI-DAD conducted an N=137 pilot MRI study between 2018 and 2020 during its Wave 1 data collection.
Originally planned as an N=200 study, the pilot study was cut short due to the Covid-19 pandemic.
Scanning took place at three sites:
1. Karnataka (National Institute of Mental Health and Neurosciences; NIMHANS, Bangalore)
2. West Bengal (Institute of Neurosciences, Kolkata)
3. Maharashtra (NM Medical Center, Mumbai)
The 55-minute 3T MRI protocol implemented at each site is summarized in the figure below.
Information on how to request data from the pilot study and what's available is here.
References:
1. Lee, J. et al. Design and Methodology of the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD). J Am Geriatr Soc 68, S5–S10 (2020).
2. Lee, J. et al. Deep phenotyping and genomic data from a nationally representative study on dementia in India. Sci Data 10, 45 (2023).
3. Aksman, L., Lynch, K., Toga, A., Dey, A. B. & Lee, J. Investigating the factors that explain white matter hyperintensity load in older Indians. Brain Communications fcad008 (2023).